15 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Prednisone 5mg/kg ... - pulmonary opacities ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... organ damage • Treatment ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
AECOPD) Obtain workup ... ventilated • CXR ... doppler, CTA • ECG ... #Exacerbation #treatment ... #pulmonary
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
- Differential Diagnosis ... level <100 pg/ml EKG ... ischemic changes CXR ... respiratory distress syndrome ... #cardiology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... mononeuritis multiplex WORKUP ... recent DAN) • EMG ... #management #treatment
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Blood cultures • CXR ... early disease) • CXR ... Clindamycin in case of PCN ... • Vasculitis (e.g ... Lung #Abscess #pulmonary
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
And Proteinuria (e.g ... insufficiency (Cr ... ), pulmonary edema ... patients • HELLP: Syndrome ... htn #obstetrics #cardiology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... ): - Hematologic ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... ECG is vital while ... acute coronary syndrome ... algorithm #management #cardiology ... #treatment #table