26 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... fluid overload, PCC ... #APML #diagnosis
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential ... K-ATPase which imports ... - Refeeding Syndrome ... #low #pathophysiology
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
Causes of Seizures ... - Differential ... Diagnosis Algorithm ... vasoconstriction syndrome ... Neurocysticercosis, PML
Causes of Sudden Cardiac Arrest
Primary Myocardial Processes (> 90%):
 • Acquired structural heart disease: CAD, Most
Causes of Sudden ... Channelopathies: Long/short ... Cardiac #Arrest #cardiology ... #differential # ... diagnosis #causes
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Scl70 (in some cases ... -70 (in some cases ... conditions - Sp-100, PML ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Causes of Pericardial ... Diagnosis Infectious ... Non-Infectious: • Rheumatologic ... #Diagnosis #Causes ... #cardiology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
myeloma, CML, AML ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential ... #Diagnosis
Medial Meniscus Bucket Handle Tear - MSK Radiology
Imaging Findings:
 • Truncation of the medial meniscus on
Handle Tear - MSK Radiology ... The "double PCL ... Case description ... Differential diagnosis ... BucketHandle #Tear #knee
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
- Compatible syndrome ... toxo IgG • CNS PCR ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Diagnosis and Pathophysiology ... Acute Coronary Syndrome ... #Diagnosis #Pathophysiology ... #causes #cardiology