16 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #HyperKalemia #Nephrology
IV Fluids - Comparison Table
Fluid - pH - Osm - Na - Cl - Other
 •
IV Fluids - Comparison ... Table Fluid - ... pH - Osm - Na - Cl ... #IVF #Comparison ... #Table #pharmacology
Crystalloid Fluids - Contents Comparison Table
Normal plasma
0.9% saline (a.k.a. "normal saline" or NS)
0.45% saline (a.k.a. 1/2
Crystalloid Fluids ... - Contents Comparison ... 2 4NS + 20 meq KCL ... #Crystalloid #Fluids ... #Table #pharmacology
IV Fluid Composition and Effects on Plasma
0.9% Saline
Ringer's Lactate
Balanced Crystalloid

#IVFluid #Composition #Plasma #comparison #Effects #nephrology #pharmacology
IV Fluid Composition ... Composition #Plasma #comparison ... #Effects #nephrology ... #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... → treat with fluid ... SaltWasting #SIADH #Pathophysiology ... #diagnosis #nephrology ... #hyponatremia #comparison
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... works by directly binding ... CaitEKulig #Digoxin #Pharmacology ... #Pathophysiology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... constipation, diarrhea; fluid ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Management of Pediatric Kidney Stones
Acute Managment:
 • Pain relief: NSAIDs, opioids
 • Facilitating passage of stone:
, Anuria - PCN ... patients - High Fluid ... alkalinisation: potassium ... alkalinization: potassium ... Management #Pediatrics #nephrology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... cyclosilicate #Potassium ... Hyperkalemia #treatment #pharmacology ... #table #comparison ... #nephrology