18 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
, autoimmune hepatitis ... ) - Autoimmune hepatitis ... syndrome Anti-Scl ... #diagnosis #table ... #rheumatology #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... Differential Diaqnoses ... hepatomegaly, hepatitis ... #diagnosis #management ... #treatment #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... Epstein-Barr Virus • Hepatitis ... Arthritis • SLE ... Obstructive Pulmonary Disease ... Myasthenia Gravis Pharmacologic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Manifestations: Malar rash ... life-threatening • Treatment ... Evolution: Chronic disease ... Erythematosus #Diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Noninfectious hepatitis ... vein thrombosis Hematologic ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... #Algorithm #hepatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... life-threatening • Treatment ... Evolution: Chronic disease ... #diagnosis #management
Lyme Disease - Diagnosis and Management Summary

Lyme Disease Epidemiology:
- Spirochete
- Reservoir: small mammals & birds
- Transmitted
Lyme Disease - Diagnosis ... Rash: distinctive ... Treatment: 1. ... cefotaxime or PCN ... #treatment
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... : > 2 • NASH, ... #differential #diagnosis ... #algorithm #hepatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... mucositis - Rash ... lesions-interstitial keratitis ... vasculitis, and SLE ... #rheumatology #