36 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... #differential #diagnosis ... #pathophysiology ... #pharmacology #
Emergency Therapy of Hyperkalemia
Therapy - Dose and Route - Onset of Action - Duration of Effect
Emergency Therapy of Hyperkalemia ... Hemodialysis #Hyperkalemia ... #management #pharmacology ... #table #treatment
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
) BRASH Treatment ... • Aggressive treatment ... of hyperkalemia ... BRASH #Syndrome #diagnosis ... #management #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
convoluted tubule (PCT ... filtered Na+/K+/Cl ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Antibiotics (Bactrim, PCN ... Elimination (see Table ... definitive guide to diagnosis ... #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... Dermatomyositis) AKI - Pathophysiology ... per day until stable ... Dialysis for severe hyperkalemia ... #Differential #Diagnosis
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... • LDH ↑ • Hyperkalemia ... Treatment of underlying ... per day until stable ... #Differential #Diagnosis
Orthopedic Essentials - Spinal Trauma and Spine Classification 
DENIS THREE COLUMN CONCEPT
Anterior column:
Middle column: PLL ... process fracture Stable ... deficit, still able ... Cauda equina Treatment ... #Orthopedics #diagnosis