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differential aflp hellp obstetrics pregnancy thrombocytopenia ttphus arthritis bleeding bruising chronic cll disease druginduced hemolysis hemostasis inherited laboratory leukemia lupus
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Elevated Liver tests ... schistocytes, DIC ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... MAHA: TTP, HUS, DIC ... Drug-associated, PCH ... Laboratory Tests ... #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Elevated Liver tests ... schistocytes, DIC ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier ... lack of GP Ib/IX ... #comparison #table ... #differential #diagnosis ... #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... should be obtained ... (to support a diagnosis ... #diagnosis #testing ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... • M > F • Affects ... phenomenon CLL Diagnosis ... #workup #oncology ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... or Qualitative defect ... cascade is intact - test ... of factor VII should ... #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
claudication, pulse deficits ... proximal muscles of shoulder ... the skin, neurologic ... drug exposure or Dx ... #Rheumatology
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