21 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
- Summary Antinuclear ... Initial screening test ... block • Sjogren syndrome ... #SLE #Summary #diagnosis ... #rheumatology #
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... cases • Sjögren syndrome ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... healthy adults, and should ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #diagnosis #differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... Liver Function Tests ... Myelodisplastic syndrome ... Psychiatric Disease ... Pruritus #primary #secondary
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
Causes of Secondary ... - Differential Diagnosis ... • Cushing’s syndrome ... Causes #Screening #Workup ... #table
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
and Systemic lupus ... clinically suspected, tests ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... table #ANA
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Classified among the secondary ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
urgent referral to secondary ... presence of metabolic syndrome ... or referral to secondary ... alcohol-related liver disease ... non-alcoholic fatty liver disease
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... erythematosus (SLE) - Antinuclear ... should be obtained ... #diagnosis #testing
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... female, asian • Systemic ... specific laboratory tests ... autoantibodies (antinuclear ... #phenotypes #workup