13 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
anemia • Cold ... Positive Coombs testing ... Test: Donath-Landsteiner ... test #cold # ... #hematology #diagnosis
Diagnosing Brucellosis
Epidemiological Exposures
- Endemic Regions
- Clinical Micro Lab Technicians
- Animal/Vaccine Exposure: Vets, Slaughterhouse workers, hunters
- Unpasteurized
Tests: - CBC ... + Chemistry: Anemia ... , Convalescent Serology ... SAT, ELISA), 16S PCR ... Criteria #Workup #Testing
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... body-like: - Neurologic ... Antinuclear #Antibody #Testing ... #differential #diagnosis ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... smear, HIV/HCV testing ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... Causes #Workup #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Drug-associated, PCH ... Defects: Sickle cell anemia ... Laboratory Tests ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... should be obtained ... the presence of anemia ... (to support a diagnosis ... #testing #Rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... SEROSITIS - RENAL - NEUROLOGIC ... - HEMOLYTIC ANEMIA ... Direct Coombs’ test ... #Diagnosis #Rheumatology
Dix-Hallpike Maneuver for BPPV

Procedure:
1. Make the patient sit on examination table, such that the shoulders would
Dix-Hallpike Maneuver for BPPV ... such that the shoulders ... 45° towards the test ... #Instructions #Diagnosis ... #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... WAIHA • CAD • PCH ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... phenomenon CLL Diagnosis ... • Neutropenia, anemia ... Transform to DLBCL, PML ... workup #oncology #hematology