13 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ANA ... • Scleroderma (Systemic ... Autoantibodies #Rheumatology ... #table
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... knees • Diffuse ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Antinuclear (ANA ... Initial screening test ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... RF test should ... #diagnosis #testing ... #Rheumatology
Abdominal Pain - Differential Diagnosis According to Localization of Abdominal Pain 

Abdominal pain can originate from
advisable to be systematic ... GI, infectious, hematologic ... An EP should prioritize ... abdominal pain (Table ... GrepMed Recommended Text
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Diagnosing Vitamin ... inadequate to diagnosis ... should be the first ... line tests for ... #Nutrition #Hematology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... clinically suspected, tests ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
female, asian • Systemic ... PET-CT Imaging (→ Diagnostic ... specific laboratory tests ... management #phenotypes #workup ... #treatment #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... adults in the west ... ’s CLL Scoring system ... #workup #oncology ... #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
: - ANA > ... months to years) Systemic ... sle #comparison #table ... #rheumatology # ... diagnosis #management