45 results
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
+ (↑ pH) • ↓ PCO2 ... tissue): • ↑ H+ (Acid ... ) • ↑ PCO2 • ... Dissociation #Curve #pathophysiology
Basics of Waveform Capnography
Waveform capnography assesses ventilation by monitoring exhaled carbon dioxide
Can use measurement and morphology
cycle to uncover pathophysiology ... regarding pulmonary pathophysiology ... CLINICAL APPLICATIONS ... Assessing for CO2 ... WAVEFORM - Critical
Blood Gas (ABG) Interpretation and Acid-Base Pathology
1- Does the patient have an acidosis or an alkalosis?
Interpretation and Acid-Base ... Look at the pCO2 ... Metabolic Equal (If pCO2 ... the change in pCO2 ... Amy Chung, MD, MSc
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

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Arachidonic acid ... #Pharmacology #Pathophysiology ... Recommended Text: Clinical
X-linked Severe Combined Immunodeficiency (SCID): Pathogenesis and clinical findings

#SCID #SevereCombinedImmunodeficiency #XLinked #pathophysiology #immunology
Immunodeficiency (SCID ... Pathogenesis and clinical ... findings #SCID ... SevereCombinedImmunodeficiency #XLinked #pathophysiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... : • Low CO2 = ... CPP) • High CO2 ... and via lactic acid ... Pressure #ICP #Pathophysiology
#ICUCard
RENAL
GFR
90-131
mL/min
((140-age)*Wt)/(72*Cr)
Glomerular Filtration Rate (Cockcroft)
CI Cr
90-131
mL/min
(CrU * volume)/CrS
Creatinine Clearance
FENa
0.0-1.0
%
((U/P Na)/(U/P Cr))*100
Fractional Excretion of Na+
Na req
mEq
(125-Na)*0.6*Wt
Required Sodium
FE Urea
Osmolar Gap ACID-BASE ... H_def 0 mEq Acid ... pCO2 = 1.5 (HCO3 ... )/HCO3 Acid base ... 70 mmHg on 100% mask
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
Pathogenesis and Clinical ... compete with uric acid ... -> Incr uric acid ... joints -> Uric acid ... Hyperuricemia #Pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Pathogenesis and clinical ... StressFractures #msk ... #orthopedics #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... fetal free fatty acid ... Intermediate fatty acid ... Maternal Support - Critical ... diagnosis #management #pathophysiology