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diagnosis hematology differential clinical workup blood bloodsmear path causes hemolysis oncology ahus analysis asplenia atypical auer auerrods bacilliformis bartonella centralpallor
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Anemias (AIHAs)
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Megaloblastic Anemia ... anemia (e.g. ... anemia Sickled ... Analysis #hematology #microscopy ... interpretation #clinical #anemia
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Anemia Intravascular ... Extravascular Hemolysis ... bilirubin LDH Peripheral ... smear Haptoglobin ... #Anemia #Laboratory
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... anemia. ... anemia is characterized ... #anemia #Hematology ... #Microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Hereditary: • Peripheral ... blood smear + DAT ... → Sickle Cell anemia ... anemia (TTP, HUS
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
Here is another peripheral ... blood smear demonstrating ... iron deficiency anemia ... Clinical #Path #Microscopy ... PeripheralBloodSmear #BloodSmear #Anemia
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
Spur-Cell Anemia ... smear showed numerous ... anemia that can ... Spur-cell anemia ... #smear
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
of macrocytic anemia ... by ordering a peripheral ... smear, a reticulocyte ... elevated, but anemia ... megaloblastic anemia
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
12-13 g/dL, • ANC ... BMP, uric acid, peripheral ... smear, reticulocyte ... ↑ Destruction (hemolysis ... Matthew Ho, MD PhD
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... treatment, her peripheral ... blood smear showed ... BloodSmear #Blood #Smear ... #Microscopy #Auer
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