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diagnosis anemia differential analysis anemias blood clinical folate folicacid hemolysis homocysteine interpretation laboratory macrocytic macrocytosis maha mds microangiopathic mma myelodysplasia
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
bilirubin LDH Peripheral ... smear Haptoglobin ... Laboratory #Testing #workup ... #diagnosis #hematology ... #hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Matthew Ho, MD PhD ... #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Smear Analysis ... #Blood #Smear # ... Analysis #hematology ... #microscopy #interpretation
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
12-13 g/dL, • ANC ... BMP, uric acid, peripheral ... smear, reticulocyte ... ↑ Destruction (hemolysis ... #hematology #workup
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... smear changes are ... #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Peripheral Smear ... for workup, including ... blood loss, Acute hemolysis ... Matthew Ho, MD PhD
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... by ordering a peripheral ... smear, a reticulocyte ... Hemorrhage or hemolysis ... #Workup #AAFP
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... the range of Peripheral ... blood smear - Shows ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... bone marrow and peripheral ... Smear: • Dysplastic ... blood smear • ... Syndromes #diagnosis #hematology
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