13 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Infection (sepsis), PE ... Differentiation #Syndrome ... #management #hematology
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... #Leukemia #Hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
EGPA • Solid cancers ... Vasculitis #dermpath #dermatology ... lesions #diagnosis #clinical ... manifestations #pathology
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease
 • Superficial Venous Thrombosis
 • Upper
vein and above)/PE ... post-thrombotic syndrome ... - Subsegmental PE ... Thrombophilia • Cancer ... management #DVT #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Orange or Hep C Clinical ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Lymphoma or other cancers ... gastric and breast cancer ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
A quick infographic on the importance of sun protection and the various results of sun damage
causes #diagnosis #dermatology ... Toxicol Appl Pharmacol ... : clinical basics ... Skin Cancer. ... CA Cancer J Clin