37 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... -> AML: Blast crises ... cutaneous plaques) AML ... smear: Blasts APML ... #Oncology #Diagnosis
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid (AML ... • Lymphoid (ALL ... Involvement - B-cell ... CD10 - T-cell ... - B-cell
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Diagnosis: • ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
in APML Epidemiology ... Incidence: common in APL ... • Induce blast cell ... Infection (sepsis), PE ... #APML #diagnosis
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-prolymphocytic leukemia (T-PLL ... Myeloid Leukemia (AML ... 🔬Tumor cells are ... Smear #Peripheral #Pathology ... #Microscopy #Clinical
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... Myelogenous Leukemia (CML ... progression to AML ... #diagnosis #hematology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
- Differential Diagnosis ... ), Heme malig (AML ... , CML, T-cell leuk ... /lymphoma, B-cell ... mastocytosis, Langerhans cell
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
typically of B-cell ... Reed Sternberg cell ... type (B cell, T ... Malignancies (eg CML ... , ALL) • Solid
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
marrow plasma cell ... M spike: • CML ... , B and T cell lymphoproliferative ... diseases, CML, ... plasmacytoma, POEMs syndrome