11 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... -> AML: Blast crises ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Incidence: common in APL ... Infection (sepsis), PE ... #APML #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... deficiency • Exposure ... progression to AML ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
older adults • Exposure ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... Transform to DLBCL, PML
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
is similar to PML ... well-defined than PML ... Diagnosis: MRI ... etiologies and PML ... syndrome of HAD
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
10d, venous (DVT/PE ... : • Clinical Suspicion ... Management: • D/c all ... reverse any warfarin exposure ... non-heparin A/C if clinical
A quick infographic on the importance of sun protection and the various results of sun damage
wavelengths #causes #diagnosis ... #dermatology #skin ... Toxicol Appl Pharmacol ... non-melanoma skin cancer: clinical ... damage in skin cells
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Low or absent NK cell ... Ferritin >500 ng/mL ... management #treatment #hematology
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
the Fingers Clinically ... trauma, and cold exposure ... seen in Reiter's syndrome ... Diseases #Abnormal #Pathology ... #Diagnosis #Clinical
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... increase in CD4+ cells ... noncompliance • Clinical ... initiation Clinical ... leukoencephalopathy (PML