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hematology management oncology leukemia activation aids algorithm associated cancer causes chronic cll damage dementia differential differentiation disorder exposure hand hiv
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... -> AML: Blast crises ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Incidence: common in APL ... Infection (sepsis), PE ... #APML #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... Myelogenous Leukemia (CML ... progression to AML ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : Overwhelming clinical ... syndrome associated ... Low or absent NK cell ... Ferritin >500 ng/mL
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... Clinical Presentation ... Fever is the main clinical ... 5000 to 10,000 ng/mL ... #Diagnosis #Management
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
is similar to PML ... well-defined than PML ... Diagnosis: MRI ... etiologies and PML ... syndrome of HAD
A quick infographic on the importance of sun protection and the various results of sun damage
wavelengths #causes #diagnosis ... #dermatology #skin ... Toxicol Appl Pharmacol ... non-melanoma skin cancer: clinical ... damage in skin cells
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... increase in CD4+ cells ... noncompliance • Clinical ... initiation Clinical ... leukoencephalopathy (PML
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
myeloid leukemia (AML ... cytopenias and AML ... median age at diagnosis ... with repeated red cell ... importance of clinical
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