36 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Drugs, Unknown cause ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... ischemia, bowel infarction ... TLS #diagnosis #management ... #hematology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Rheumatologic ... by culture or serology ... Aspergillosis Pathophysiology ... Diagnosis: • Serology ... Fungal #Diagnosis #Management
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
Diagnosis and Management ... Coccobacillus - Zoonotic Infection ... eye; unilateral symptoms ... conditions Diagnosis: Serology ... Culture & GS, PCR Treatment
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Antimicrobial treatment ... status, and focal neurologic ... Demyelinating disease caused ... confusion, and focal neurologic ... InfectiousDiseases #Neurology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... Visual or auditory symptoms ... conjunction with symptoms ... diagnosis and treatment ... BEE #Syndromes #neurology
The rationale for aggressive treatment of generalized status epilepticus was described previously here.  In short,
for aggressive treatment ... epilepticus which may cause ... epilepticus may cause ... hyperthermia, myocardial infarction ... #Management #Neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... • Treatment of ... Syndrome #diagnosis #management ... #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... - Emergency Causes ... axial T1 and T2 Treatment ... #neurology