70 results
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain with rest ... motion (relieved by rest ... > Stiffness is short-lived ... JointDisease #JointPain #Diagnosis ... #pathophysiology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
between deficiencies and ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
of hands/feet, ... : CLINICAL DIAGNOSIS ... history, exam and ... imaging Treatment ... #management #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
anterior chest wall, parts ... Diagnosis: ... lower jaw Treatment ... the best response ... SAPHO #Syndrome #Rheumatology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... RTX • Short-term ... #rheumatology # ... hematology
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
: Pathogenesis and ... of lumbosacral joint ... (Stork test) ... Spondylolisthesis #MSK #diagnosis ... #pathophysiology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... and with motion ... improves quickly with rest ... #Pain #MSK #rheumatology ... #differential #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Spherocytes • Treatment ... transient hemolysis • Treatment ... Plasmapheresis - VA Joint ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
: Pathogenesis and ... joints are inflamed ... , ridging, oil spots ... PsoriaticArthritis #pathophysiology ... #diagnosis #signs