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rheumatology anemia chronic druginduced hemeonc lupus lymphocytic mds myelodysplastic comparison dil emergencies hemophagocytic hlh lymphohistiocytosis myelodysplasia oncologic syndrome syndromes table
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Summary myelo ( ... dys- (abnormal) -plastic ... transformation to acute leukemia ... #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... non-Hodgkin lymphoma SLL ... aplasia • ITP ... microglobulin Treatment ... #oncology #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Consider stem cell ... to MDS or acute leukemia ... #management #treatment ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... uw_IMresidency #CLL ... #oncology #hematology ... #hemeonc #diagnosis ... #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis ... #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... terbinafine, thiazidic, PPI ... life-threatening • Treatment ... Usual therapeutic management ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
lymphoma, B-cell ... Autoimmune diseases: SLE ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... Usually myeloid leukemias ... ± tocilizumab; call ... #HemeOnc #Diagnosis
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Epidemiology: -10% of all ... is rare in DIL, SCLE-DIL ... terbinafine, thiazidic, PPI ... #diagnosis #treatment ... #management
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