11 results
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management
 • Giant Cell Arteritis (GCA)
 •
for Treatment & ... Polyangiitis (GPA ... Polyangiitis (EGPA ... #ACR2021 #Guidelines ... #algorithm #rheumatology
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (GPA ... polyangiitis (EGPA ... associated with PR3 ... > PR3 Dr. ... MPO #PR3 #Diagnosis
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA ... Algorithm - ACR ... #Polyangiitis #GPA ... #Treatment #ACR2021 ... #Guidelines #algorithm
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Active
Polyangiitis (EGPA ... ) - ANCA Vasculitis ... alone in select pts ... #Treatment #ACR2021 ... #Guidelines #algorithm
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis

MPA → usually p-ANCA
GPA → usually c-ANCA
EGPA →
and Differential Diagnosis ... GPA → usually ... c-ANCA EGPAANCA ... PR3) X-ANCA (elastase ... ANCA Vasculitis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Negative IF): • PR3 ... GPA >>> MPA > eGPA ... GPA Stanford Internal ... #differential #diagnosis ... #algorithm #rheumatology
Frequency of ANCA Positivity in Different Conditions
ANCA-Associated Vasculitis
 • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5%
GPA - PR3-ANCA 75% ... • MPA - PR3-ANCA ... • EGPA - PR3- ... - PR3-ANCA 10%, ... #MPO #PR3 #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
proteinase 3 (PR3 ... in >90%, MPO > PR3 ... 60% • GPA: ... 80% (80-90% have PR3 ... (Dx: GPA, EGPA,
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
): GPA (granulomatous ... Renal Syndromes (PRS ... defining feature, PRS ... of PRS: Biopsy ... @MithuRheum #PRS
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
proteinase 3 (PR3 ... in > 30 / MPO > PR3 ... hemoptysis, MPO > PR3 ... 60/ GPA (Granulomatosis ... 90 percent have PR3