14 results
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (GPA ... polyangiitis (EGPA ... vasculitis - MPO ... vasculitis - MPO ... MPO #PR3 #Diagnosis
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management
 • Giant Cell Arteritis (GCA)
 •
Polyangiitis (GPA ... Polyangiitis (MPA ... Polyangiitis (EGPA ... #ACR2021 #Guidelines ... #algorithm #rheumatology
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis

MPA → usually p-ANCA
GPA → usually c-ANCA
EGPA →
and Differential Diagnosis ... p-ANCA GPA → usually ... c-ANCA EGPA → ... P-ANCA (MPO) ... C-ANCA (PR3) X-ANCA
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA ... ) - ANCA Vasculitis ... #ANCA #Vasculitis ... #Management #Treatment ... #ACR2021 #Guidelines
Frequency of ANCA Positivity in Different Conditions
ANCA-Associated Vasculitis
 • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5%
GPA - PR3-ANCA 75% ... • MPA - PR3-ANCA ... • EGPA - PR3- ... - PR3-ANCA 10%, ... #PR3 #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Negative IF): • PR3 ... GPA >>> MPA > eGPA ... • MPO-ANCA (P-ANCA ... ): eGPA, MPA >>> ... GPA Stanford Internal
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Active
Polyangiitis (EGPA ... ) - ANCA Vasculitis ... alone in select pts ... #Treatment #ACR2021 ... #Guidelines #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
proteinase 3 (PR3 ... > PR3 60% • GPA ... 80% (80-90% have PR3 ... Vasculitis: + MPO-ANCA ... (Dx: GPA, EGPA,
2021 ACR/VF Guidelines for Management of Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA)

#Granulomatosis #Polyangiitis #GPA
2021 ACR/VF Guidelines ... Polyangiitis (GPA ... #Polyangiitis #GPA ... #ACR2021 #Management ... #vasculitis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
): GPA (granulomatous ... Renal Syndromes (PRS ... defining feature, PRS ... of PRS: Biopsy ... @MithuRheum #PRS