10 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... child * Severe cases ... exchange 2) Fatty liver ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Diagnosis Hepatocellular ... Toxic: Medication, Pregnancy ... #Causes #Acute ... #algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Highest • Bone • Liver ... Intestine - Other causes ... - Drugs - Pregnancy
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal ... Pregnancy) - Low ... #Algorithm #Causes ... #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Algorithm Severe ... • Wilson's • Pregnancy ... Bile Ducts • PSC ... #Algorithm #Causes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... melanoma, myeloma • Pregnancy ... #algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... first trimester pregnancy ... • Treatment algorithms ... #diagnosis #management ... #hematology