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differential injury acute biliary cirrhosis hematology workup acutekidneyinjury alkaline alp cholangitis classification coagulation dic disorders disseminated elevation hepatitis intravascular kidney
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
PBC if 2/3 criteria ... Liver biopsy findings ... consistent with PBC ... #PBC #Primary ... #Algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Diagnosis Hepatocellular ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Causes of Acute ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... #algorithm #hepatology
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
- TTE/liver fxn? ... - BMP, cap, CBC ... pre-renal) - Urinary ... #Nephrology #Diagnosis ... #Algorithm #Causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... unclear, or if a primary ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... #Algorithm #Causes
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
cardiorenal syndrome) • Liver ... tubular necrosis (causes ... : sepsis, meds, ... Classification #diagnosis ... #nephrology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Treatment: • Treat primary ... cause • Correct ... #Coagulation #diagnosis ... #causes #treatment
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