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diagnosis management algorithm classification differentiation emergencies erythematosus hemeonc hodgkins lad leukemia lupus lymphadenopathy lymphoma mds myelodysplasia myelodysplastic oncologic plasmacytoma rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... : Blast crises ... + distinctive primary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Reed-Sternberg Cells ... Hodgkin's Lymphoma #Diffuse ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... • Induce blast cell ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
abdomen if abdominal pain ... syndrome): - Hematologic ... Treat underlying cause ... Lower-extremity weakness, urinary ... “big & sticky” cells
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... the context of primary ... pneumonitis • Diffuse ... Arthritis: • Joint pain ... : • Chronic B-cell
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... hemolytic anemia • Pain ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
presents with pain ... except for the primary ... UPEP, Serum IFE, FLC ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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