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diagnosis hematology algorithm management workup abdominal allergy anemia apml classification differentiation eosinophilia erythematosus gastroenterology hodgkins lad leukemia lupus lymphadenopathy lymphoma
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Age > 50 • Chronic ... Reed-Sternberg Cells ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... -> AML: Blast crises ... + distinctive primary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... dysfunction • PSC ... Ovarian CA Diffuse ... #Chronic #Causes ... #Differential #
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Reticulocytosis • Primary ... RA, SLE, PRV, Chronic ... , Target Cells ... #Hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential ... - DRESS - AIN ... Hypereosinophilic Syndrome - Chronic ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... initiation • Differential ... fluid overload, PCC ... diagnosis #management #hematology ... #oncology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... 2nd pass = Chronic ... 3rd pass = Primary ... cell activation ... #Diagnosis #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Too many cells in ... Better call hematology ... normal/high - Chronic ... Algorithm #workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... Marrow Failure • Chronic ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... the context of primary ... Arthritis: • Joint pain ... with Lupus: • Chronic ... B-cell activation
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