15 results
Mallet Finger
Absence of a fracture does NOT exclude Mallet finger, the extension function of the DIP
Finger deformity caused ... MH/CCF/CWRU EM ... Radiology #XRay #Diagnosis ... #Management #Hand ... #Orthopedics #MSK
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... #management #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Cytopenia +++ (Plt ... Treatment: • ... #management #treatment ... #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
and Management ... ♀, ↑Age, ESRD Pathophysiology ... heparin-PF4 complex → plt ... #Management #Treatment ... #Hematology #HemeOnc
Boxer's Fracture - ED Management
Be sure to assess for wounds in patients with fractures of the
prophylactic antibiotic treatment ... Discharge home with orthopedic ... MH/CCF/CWRU EM ... Radiology #XRay #Diagnosis ... #Orthopedics #MSK
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... #cerebritis #diagnosis ... #management #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... and Management ... nonimmune hemolysis MSK ... , or any other cause ... vasculitis Treatment