28 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... biliary cirrhosis (PBC ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Management - GrepMed ... Handbook Clinical ... Perforation) Pathophysiology ... #management #treatment ... #infectiousdiseases
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
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and Management ... extrapulmonary cases Clinical ... Signs/Symptoms: ... decreased reflexes Pathophysiology ... intervention CMC
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... not feasible CMC
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Cytopenia +++ (Plt ... salmonella, ...), Parasites ... #management #treatment
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... #management #pathophysiology
Trypanosomiasis - Trypanosoma cruzi Life Cycle
1) Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in
Clinical manifestations ... Tcruzi #LifeCycle #diagnosis ... #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Atorvastatin Diagnosis ... IU/I • SAMS clinical ... toxicity #myopathy #diagnosis ... #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... fluid overload, PCC ... #management #hematology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... Anti-PL12, Anti-PL7 ... Polymyositis #PM #Diagnosis ... #Pathophysiology ... #Signs #Symptoms