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diagnosis hematology liver syndrome aflp algorithm apml coagulation crisis dic differentiation disseminated encephalopathy fatty gap globulin hepatitis hospitalization injury intravascular
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
of chronic kidney ... disease, Acute ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... cardiac muscle, kidneys ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Liver #Pregnancy #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... protein C and S Pathophysiology ... Treat primary cause ... #treatment #management ... #hematology
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
- Pathophysiology ... prolonged rest can cause ... blood loss or acute ... #pathophysiology ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Viral infections (acute ... Thalassemia, Sickle cell anemia ... inflammation (acute ... Gap #ProteinGap #differential ... #diagnosis #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Reversible course Differential ... the underlying cause ... Syndrome #diagnosis #management ... #neurology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Renal Crisis: 1) Acute ... kidney injury ... microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... #rheumatology #nephrology
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