10 results
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift: • Alkalosis ... • Refeeding syndrome ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology ... #low #potassium
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... , Bartter's syndrome ... Hypokalemia #Causes #differential ... #diagnosis #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... Thiazide or loop diuretics ... other • Severe potassium ... #Differential # ... Diagnosis #Causes #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
loop or thiazide diuretics ... , Gitelman syndrome ... of sodium and potassium ... urine #Algorithm #nephrology ... #differential #
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... - Metabolic Alkalosis ... : Emesis, Diuretics ... diagnosis #Algorithm #differential ... #potassium #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Metabolic alkalosis ... disequilibrium syndrome ... irrigation • Management ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... ratio 0.5%) Differential ... Rhabdomyolysis Treatment ... #diagnosis #nephrology ... #management #pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... iniury, Compartment syndrome ... Monitor potassium ... Loop diuretics for
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Monitor potassium ... Loop diuretics for ... #nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... Supportive Care: Diuresis ... APML #diagnosis #management