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diagnosis algorithm differential hematology pbc management causes cirrhosis cholangitis oncology workup abnormal alkaline elevation laboratory phosphatase psc tests transaminitis treatment
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... , PSC, Alcoholic ... - CBD stone, Biliary ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... ALP - Biliary ... #FunctionTest #LFTs ... Transaminitis #diagnosis #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Highest • Bone • Liver ... - Drugs - Primary ... biliary Cholangitis ... - Other biliary ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Pathophysiology ... obstruction • ALP ... or higher • Liver ... diagnosis #workup #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Elevated ALP 2. ... Liver biopsy findings ... #PBC #Primary ... Diagnosis #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
, PSC, IgG4, HLH ... Extrahepatic - Biliary ... Choledocholithiasis, Biliary ... - Obstruction: Biliary ... diagnosis #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Bile Ducts • PSC ... Duct Stone • Biliary ... • Others #LFTs ... #Hepatology #LiverEnzymes
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... Pathophysiology ... #Primary #Biliary ... #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... , biliary epithelium ... Conjugated/DBili) - Biliary ... Function #Tests #LFTs ... Interpretation #diagnosis #hepatology
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