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hematology diagnosis causes hemolysis agglutinin algorithm autoimmune classification disease extravascular intravascular microangiopathic monoclonal oncology paraproteinemias pathology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - ... Table Warm AIHA ... AHA (16-32%) • ... #Anemia #AIHA # ... #Table #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... • Cold AIHA ... anemia • ... Shearing • MAHA ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Fragmentation - MAHA ... , Cold AIHA, Transfusion ... Defects: Sickle cell anemia ... Peripheral Blood Smear
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... @mjcascio #MAHA ... #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... Hypersplenism • AIHA ... : warm, cold, drug ... Intravascular Causes: • MAHA ... #Anemia #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... Viral Infection Clinical ... anemia • Cold ... IgM) • Blood smear ... #anemia #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt ... Coagulopathy) SMZL: • AIHA ... • Coombs (-) hemolytic ... anemia due to cold ... #Monoclonal #Differential
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