13 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV ... changes), high MCV anemia ... dysplasia on the smear ... #Workup #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Peripheral Smear ... Out Secondary Causes ... smear • Bone marrow
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
12.5, WBC 14, Plt ... The table below ... Treatment is tetracycline ... initiation of treatment ... microscopy #pathology #clinical
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... -> AML: Blast crises ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... Treatment: ... result from low blood
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... • Peripheral smear ... Treat primary cause ... #hematology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
infectious disease caused ... Blood (platelets ... positive serology, smear ... others: AV blocks, PVC ... thick peripheral smears
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... of high parity blood ... without other cause ... : 33% • Treatment ... diagnosis #comparison #table
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess - Clinical ... Leukocytosis, anemia ... • Sputum/Blood ... #differential #causes
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Pernicious anemia ... deficiency • blood ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology