11 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... anemia Sickled ... #hematology #microscopy ... interpretation #clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Autoimmune: Warm AIHA, Cold ... Hemoglobin Defects: Sickle ... cell anemia, Thalassemias ... - Peripheral Blood ... Smear ↑ abnormal
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... disease, Artifact Sickle ... Cell Agglutinate: Cold ... cold hemoglobinuria
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
- A 31-year-old ... smear showed numerous ... , a form of hemolytic ... #NEJM #clinical ... #smear
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... anemiaCold ... smear - RBC agglutination ... sensitize red blood ... #anemia #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
practices that could ... plateletcount), peripheral blood ... smear, HIV/HCV ... changes), high MCV anemia ... dysplasia on the smear
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
smears the small ... autosplenectomy in sickle ... can be found in hemolytic ... #Clinical #Path ... #BloodSmear #Blood
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form ... #Leukemia #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... Anticonvulsants - Gold ... • ↓ WBC • ↓ PLT ... result from low blood ... #oncology #hematology