12 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... lymphoid organs When Cancer ... ) CLL Symptoms: ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... aplasia • ITP ... microglobulin Treatment ... ’s lymphoma or acute ... diagnosis #workup #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... = funny-shaped cells ... transformation to acute ... Allogeneic stem cell ... #hematology #oncology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Disease, Sickle Cell ... Pancreatic Pseudocyst, Cancer ... - Sophia Hayes MD ... #algorithm #hepatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Consider stem cell ... Can progress to MDS ... or acute leukemia ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Hypocellular/Hypoplastic MDS ... • ↓ WBC • ↓ PLT ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... Causes • Anemia • Aplastic ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology ... #oncology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... ) • Use of B-cell ... > 3 mg/dL) or acute ... liver failure ... Indications #management #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... fluid overload, PCC ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
myeloma • Plasma cell ... Sarcoidosis) • Liver ... ovarian tumors, lung cancers ... Thalassemia, Sickle cell ... inflammation (acute