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diagnosis hematology management algorithm anemia causes differential myelodysplastic chronic cll coagulation dic disseminated gap globulin injury intravascular lymphocytic myelodysplasia protein
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... transformation to acute ... leukemia Management ... Myelodysplastic #Syndrome #MDS ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... aplasia • ITP ... microglobulin Treatment ... ’s lymphoma or acute ... diagnosis #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Acute leukemias ... ALL (Acute Lymphoblastic ... Blasts APML (Acute ... lymphoid organs When Cancer ... #Hematology #Oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Consider stem cell ... Can progress to MDS ... or acute leukemia ... #hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Disease, Sickle Cell ... Pancreatic Pseudocyst, Cancer ... - Sophia Hayes MD ... #algorithm #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... • ↓ WBC • ↓ PLT ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... Syndromes #diagnosis #hematology ... #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... promyelocytic leukemia ... Schistocytes, helmet cells ... DIC • Severe Liver ... + Bleeding Treatment
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
myeloma • Plasma cell ... leukemia • Solitary ... Sarcoidosis) • Liver ... ovarian tumors, lung cancers ... : Lymphoma, Leukemia
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... clonal evolution to acute ... myeloid leukemia ... with repeated red cell ... #algorithm #hematology
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