4 results
diagnosis hematology management causes coagulation differentiation disseminated emergencies leukemia oncologic syndrome
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... smear: Blasts APML ... Fibrinolysis & DIC ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... fluid overload, PCC ... #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... malignancy (Especially acute ... Schistocytes, helmet cells ... + Bleeding Treatment ... #Disseminated #Intravascular
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... G6PD first) DIC ... (disseminated intravascular ... “big & sticky” cells ... #HemeOnc #Diagnosis
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