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hepatology differential injury causes transaminitis acute aih antibodies associations autoantibodies biliary cholangitis cirrhosis dermatology dili diseases disorders druginduced elevated gap
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
- Differential Diagnosis ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... Causes #Acute #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Ischemia • Autoimmune ... Bile Ducts • PSC ... • Alcoholic hepatitis ... • Others #LFTs
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... - Infection (EBV ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... Algorithm for Transaminitis ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
A/B/C/D/E, EBV, ... Other: NAFLD, Autoimmune ... #hepatology #algorithm ... Transaminitis #LFTs ... #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... HBV, HCV, HEV, EBV ... : Autoimmune hepatitis ... #algorithm #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... disease to acute liver ... hepatocellular pattern of liver ... upper limit of normal ... #Hepatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
hepatitis Anti-CCP ... Dermatomyositis Anti-LKM (liver ... biliary cirrhosis (PBC ... Associations #diseases #diagnosis ... #table #rheumatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... HBV, HCV, HEV, EBV ... steatosis • Autoimmune ... #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... Diagnosis: • ... or higher • Liver ... : • Viral hepatitis ... #workup #hepatology
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