28 results
diagnosis hematology differential management oncology algorithm reactions treatment workup ana anemia antibody antinuclear comparison disorders nuclear patterns product syndrome transfusion
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... pattern: - PBC ... , SSc, PBC/SSc OS ... , PBC/SjS OS ... differential #diagnosis #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
) - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting ... diagnosis #workup #hepatology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Tamponade Pulmonary ... Water - Pus - Blood ... Vasculature: - PE - Pulmonary ... Transverse myelitis • Hematology ... #pulmonary
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
for decreased PLT ... plateletcount), peripheral blood ... smear, HIV/HCV testing ... for decreased PLT ... #Workup #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
INDICATIONS FOR TESTING ... • Peripheral blood ... for secondary causes ... eosinophilia (common causes ... Differential #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... Paraneoplastic (e.g., RCC ... , HCC, uterine fibroids ... Diagnosis #Algorithm #hematology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
pericarditis • Hepatic: PBC ... calcinosis • Pulmonary ... disease), PAH (pulmonary ... Scleroderma #SSc #rheumatology ... signs #symptoms #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Positive Coombs testing ... Immunoglobulin M (IgM) • Blood ... Hemoglobinuria (PCH ... sensitize red blood ... hemolytic #anemia #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... fluid overload, PCC ... diagnosis #management #hematology
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