26 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
activity Anti-Ro ... block • Sjogren syndrome ... Treatment: • ... Summary #diagnosis #rheumatology ... #management
Indications for ERCP
1. Biliary Tract Diseases:
 • Biliary obstruction: Choledocholithiasis, Malignant biliary strictures, Benign biliary strictures
biliary strictures (PSC ... pancreatitis (treatment ... fluid collections (PFC ... pancreatoscopy, Drainage of PFC ... #Indications #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... Antiribosomal P, APLA, PAC ... activity • C3 ... Erythematosus #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... : Arterial (MCC-small ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... Cerebrovascular Disease ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Organomegaly+↑RBC/plt ... WAIHA • CAD • PCH ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... reported (eg AIH-PBC ... regarding need for treatment ... azathioprine (check TPMT activity ... AIH #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
staining, NAA (PCR ... Tuberculosis Treatment ... Initiating Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB