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hepatology blood differential oncology product reactions syndrome treatment aclf aflp aih apml autoimmune bleeding bruising causes chronic cirrhosis coagulation common
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... EmoryGastroHep #ACLF #Acute ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... #Pregnancy #hepatology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria ... Sweet Syndrome (Acute ... respiratory or gastrointestinal ... count >10 x 10^3/pL ... #Hematology #Dermatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... Hepatitis (eg Viral) Management ... #Management #Hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Presentation: Subacute-Acute ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... fluid overload, PCC ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... DIC • Severe Liver ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... ALL (Acute Lymphoblastic ... disease, including gastrointestinal ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presents as an acute ... Diagnosis via genetic ... lymph node, or liver ... #management #treatment ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... of the gums and gastrointestinal ... • Warfarin • Acute ... disease • Acute ... #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Bronchiectasis • Gastrointestinal ... disease • Liver ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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