11 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Diagnosis Algorithm ... Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC ... #diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Diagnosis Algorithm ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... diagnosis #algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... #Diagnosis #Algorithm ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Injury #Differential ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Diagnosis Algorithm ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... #Diagnosis #Algorithm
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
PBC if 2/3 criteria ... Elevated ALP 2. ... consistent with PBC ... #PBC #Primary ... #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... obstruction • ALP ... or higher • Liver ... bile ducts Differential ... #workup #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... : Liver Injury ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... injury, though ... reported (eg AIH-PBC ... Anti-LKM & Anti-ALC ... #Management #Hepatology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
to Acute Kidney Injury ... - TTE/liver fxn? ... AKI #Nephrology #Diagnosis ... #Algorithm #Causes ... #Differential