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hematology symptoms causes syndrome systemic disease erythematosus joint lupus pain pulmonary apml arteritis arthritis autoantibodies behcet bone bronchiectasis cardiology classification
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
Hemoptysis - Differential ... Diagnosis Framework ... Kaposi's sarcoma • Rheumatologic ... / Autoimmune: ANCA-Assoc ... Goodpasture's, SLE
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... skin thickening Signs ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Myositis 4% - Lung ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... #Rheumatology
Bronchiectasis - Permanent dilation of an airway WHAT CAN YOU SEE ON CT? 1) Lack of tapering of
WHAT CAN YOU SEE ... Obstruction 6) Rheumatologic ... /Autoimmune diseae ... Bronchiectasis #pulmonary #diagnosis ... #differential #
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Generally affects long ... predispose to other orthopedic ... dz difficult to see ... #diagnosis #causes ... #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... Diagnosis Framework ... noninflammatory Signs ... #Diagnosis #MSK ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... solid cancers • Autoimmune ... diseases: SLE++ ... #management #treatment ... #summary #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC ... #management #hematology ... #oncology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis is an autoimmune ... rheumatoid arthritis, SLE ... life-threatening Differential ... - Peek sign ... #management #neurology
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