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hematology ana antibody differential nuclear patterns anemia aplastic cytoplasmic differentiation mds myelodysplasia myelodysplastic syndrome syndromes
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... #Antibody #Testing ... #differential #diagnosis ... #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... count • ↓Hg & PLT ... smear: Blasts APML ... #Hematology #Oncology ... #Diagnosis
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Testing - Nuclear ... pattern: • SSc, PBC ... dots pattern: • PBC ... #differential #diagnosis ... #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... fluid overload, PCC ... Differentiation #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Treatment: Goals: Treating ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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