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diagnosis ana antibody antinuclear nuclear testing acidosis apml autoimmune classification cytoplasmic differentiation elevation hematology lactate lactic myopathy myositis oncology syndrome
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
: - SSc, PBC/ ... : - PBC, DM, ... , PBC/SjS OS ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Scl70 (in some cases ... : • SSc, PBC/SSc ... : • PBC, DM, other ... #differential # ... diagnosis #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... slow onset and pattern ... statins - probably caused ... Other Diseases: • PBC ... #differential #
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