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diagnosis treatment anemia aplastic apml classification coagulation dic differentiation disseminated drugrelated exanthema flexural hemophagocytic hlh intertriginous intravascular lymphohistiocytosis lymphoma photo
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma - Clinical ... Lymphoma (90-95% of cases ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Cytopenia +++ (Plt ... Hemopathies+++: Hodgkin ... Lymphohistiocytosis #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Release from blast cells ... • Induce blast cell ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Schistocytes, helmet cells ... Treat primary cause ... #treatment #management ... #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... UPEP, Serum IFE, FLC ... macroglobulinemia • Non-Hodgkin ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 49M +burning rash groins/buttocks (pic in next thread) x 1d.
groins/buttocks (pic ... MCQ highlights a case ... - symmetrical, well-demarcated ... Exanthema #rash #clinical ... #photo #dermatology
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