16 results
diagnosis differential rheumatology hepatology antibody antinuclear nuclear patterns workup aih airway algorithm anemia aplastic apml biliary challenges cholangitis cirrhosis classification
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... pattern: - PBC ... : - PBC, SSc ... , PBC/SSc OS, PBC ... ARUPConsult @ARUPLabs #ANA
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Biliary Cirrhosis (PBC ... ) - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... Bile Ducts • PSC ... • Cirrhosis (any ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... BryanCUlrich #Autoimmune ... AIH #Diagnosis #Management ... #Hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... by vasculopathy and ... pericarditis • Hepatic: PBC ... Scleroderma #SSc #rheumatology ... signs #symptoms #testing
Predicting an anatomically and/or physiologically challenging airway is not a straightforward task by any stretch of
elective surgery setting ... and may not be ... emergency airway management ... prediction models only focus ... Diagnosis #EM #PCC
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
cell adhesion and ... : leukocytosis and ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... gastric tumors • Hematology ... differential #diagnosis #hematology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody Testing ... pattern: • SSc, PBC ... dots pattern: • PBC ... ARUPConsult @ARUPLabs #ANA ... Antinuclear #Antibody #Testing
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... solid cancers • Autoimmune ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
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