35 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... , PBC/SSc OS, PBC ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... smear, HIV/HCV testing ... function test, ANA ... changes), high MCV anemia ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting ... #workup #hepatology
Predicting an anatomically and/or physiologically challenging airway is not a straightforward task by any stretch of
elective surgery setting ... management. ... prediction models only focus ... #Diagnosis #EM # ... PCC #Heaven #Criteria
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential Diagnosis ... Cold AIHA • PCH ... immune-complex hemolytic anemia ... #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... • Ischemia • Autoimmune ... Bile Ducts • PSC ... • Cirrhosis (any ... #Algorithm #Causes
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral infection, autoimmune ... anemia • Cold ... Positive Coombs testing ... CLL (older) • Autoimmune ... #hematology #diagnosis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... : Auto-Nuclear ANA ... BryanCUlrich #Autoimmune ... #Management #Hepatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Cr >2 mg/dL or CC ... 40 ml/min A - Anemia ... autoimmune diseases ... Gammopathies #MGUS #diagnosis ... #hematology #oncology