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diagnosis rheumatology antinuclear differential nuclear patterns syndrome aih anemia aplastic apml classification cytoplasmic dermatology differentiation hemophagocytic hepatitis hepatology hlh hodgkins
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... , PBC/SSc OS, PBC ... ARUPConsult @ARUPLabs #ANA ... #Testing #Nuclear
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... regarding need for treatment ... AIH #Diagnosis #Management ... #Hepatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear ... pattern: • SSc, PBC ... dots pattern: • PBC ... #Testing #Nuclear
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Renal Failure Treatment ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... solid cancers • Autoimmune ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Management Summary ... Prevalence: 1-2 cases ... autoimmune response ... disorders • Testing ... antibody that works
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
• Genital, anal ... antiorthopoxvirus IgM antibody ... Respiratory distress Treatment ... MPOX #Diagnosis #Management ... #Dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Immunosuppression • Autoimmune ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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