26 results
diagnosis hepatology rheumatology differential primary algorithm biliary pbc treatment syndrome antibody antinuclear cholangitis hepatitis nuclear patterns summary workup aih airway
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary Cirrhosis ... pregnancy Diagnose PBC ... specific ANAs (e.g ... consistent with PBC ... #PBC #Primary
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
(PBC) - Summary ... PBC Epidemiology ... 30-65 years PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary Cirrhosis ... relative with PBC ... cell mediated autoimmune ... Cholestasis #PBC ... Pathophysiology #hepatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... pattern: - PBC ... : - PBC, SSc ... , PBC/SSc OS, PBC ... ARUPConsult @ARUPLabs #ANA
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
) PSC is a chronic ... • CIRRHOSIS - ... liver disease management ... Cholangitis #diagnosis #management ... #summary #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... (any) • Congenital ... Diagnosis #Algorithm #Causes
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... microsomal) - Autoimmune ... Primary biliary cirrhosis ... (PBC) Anticentromere ... diagnosis #table #rheumatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... hepatitis: < 1 • Cirrhosis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... : Auto-Nuclear ANA ... AIH #Diagnosis #Management ... #Hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... by vasculopathy and ... pericarditis • Hepatic: PBC ... Scleroderma #SSc #rheumatology ... signs #symptoms #testing
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