11 results
diagnosis differential antibody antinuclear patterns workup aih anemia aplastic apml classification cytoplasmic differentiation disorders gap globulin hemophagocytic hepatitis hepatology hlh
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... - Nuclear and Cytoplasmic ... , PBC/SSc OS, PBC ... ARUPConsult @ARUPLabs #ANA ... differential #diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody Testing ... pattern: • SSc, PBC ... : • PBC, DM, other ... Antinuclear #Antibody #Testing ... differential #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
smear, HIV/HCV testing ... function test, ANA ... thrombocytopenia is unclear ... or if a primary hematologic ... #Workup #hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... Autoantibodies: Auto-Nuclear ... AIH #Diagnosis #Management ... #Hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... by vasculopathy and ... pericarditis • Hepatic: PBC ... Scleroderma #SSc #rheumatology ... signs #symptoms #testing
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
cell adhesion and ... : leukocytosis and ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... gastric tumors • Hematology ... differential #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... solid cancers • Autoimmune ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
petechiae Causes ... • ↓ WBC • ↓ PLT ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Immunosuppression • Autoimmune ... Lymphoma (90-95% of cases ... classification #hematology ... #oncology #management
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